Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825761 | 0.88 | TP53 (0.43) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11829272 | 0.88 | TP53 (0.40) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11826484 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11676368 | 0.83 | TSHR (0.45) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11827569 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11676164 | 0.81 | MEN1 (0.50) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11822816 | 0.78 | TP53 (0.45) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11825771 | 0.78 | TP53 (0.42) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11836303 | 0.76 | NPC1 (0.38) | ALDH1A1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11834659 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRGLATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974178-A | POLYESTER, POLYAMIDE, POLYACRYLONITRILE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |