Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971662 | 0.91 | ALDH1A1 (0.39) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11826484 | 0.88 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11825771 | 0.85 | TP53 (0.42) | ALDH1A1GLATSHRTP53NR1H2 | |
| SCHEMBL11679217 | 0.85 | LMNA (0.44) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11829445 | 0.83 | KCNH2 (0.40) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11678680 | 0.83 | MEN1 (0.48) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL11671530 | 0.83 | TDP1 (0.40) | ALDH1A1GLATSHRTP53NR1H2 | |
| SCHEMBL8942110 | 0.80 | ALDH1A1 (0.44) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11830975 | 0.79 | TP53 (0.41) | ALDH1A1GLATSHRTP53KCNH2 | |
| SCHEMBL11828887 | 0.77 | NPC1 (0.40) | ALDH1A1TP53KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974178-A | POLYESTER, POLYAMIDE, POLYACRYLONITRILE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-08-10 | — | — | US | disclosed |