Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819424 | 0.84 | KMT2A (0.41) | KMT2ASMN1; SMN2CA12CA2RAB9A | |
| SCHEMBL11821357 | 0.81 | CNR2 (0.48) | SMN1; SMN2CNR2TAS2R14CA12CA2 | |
| SCHEMBL11815261 | 0.79 | CNR2 (0.46) | SMN1; SMN2CNR2TAS2R14CA12CA2 | |
| SCHEMBL11827334 | 0.79 | CNR2 (0.48) | SMN1; SMN2CNR2TAS2R14CA12CA2 | |
| SCHEMBL11829733 | 0.76 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2CA12CA2RAB9A | |
| SCHEMBL11819862 | 0.76 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2CA12CA2RAB9A | |
| SCHEMBL11822899 | 0.74 | SMN1; SMN2 (0.44) | KMT2ASMN1; SMN2CNR2TAS2R14CA12 | |
| SCHEMBL11822163 | 0.72 | CA2 (0.47) | KMT2ASMN1; SMN2CNR2TAS2R14CA12 | |
| SCHEMBL11818580 | 0.72 | CA2 (0.47) | KMT2ASMN1; SMN2CNR2TAS2R14CA12 | |
| SCHEMBL11816329 | 0.72 | CNR2 (0.49) | SMN1; SMN2CNR2TAS2R14CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |