Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829733 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11173484 | 0.80 | KMT2A (0.77) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11816670 | 0.77 | S1PR3 (0.50) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11817543 | 0.77 | S1PR3 (0.50) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11829232 | 0.76 | KMT2A (0.42) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11817753 | 0.76 | CA9 (0.50) | SMN1; SMN2CA12CA2RAB9ACA9 | |
| SCHEMBL11816370 | 0.76 | CA9 (0.50) | SMN1; SMN2CA12CA2RAB9ACA9 | |
| SCHEMBL11596686 | 0.75 | KMT2A (0.79) | SMN1; SMN2KMT2ACA12CA2RAB9A | |
| SCHEMBL11816623 | 0.75 | TAS2R14 (0.62) | KMT2APTGESALDH1A1 | |
| SCHEMBL11820143 | 0.75 | VCAM1 (0.49) | SMN1; SMN2KMT2ACA12CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |