Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831156 | 0.89 | TP53 (0.54) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL11825378 | 0.85 | TP53 (0.65) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL11828243 | 0.70 | MEN1 (0.64) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL11836202 | 0.70 | CYP1A2 (0.60) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL3457025 | 0.70 | TRPM8 (0.67) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL7776521 | 0.69 | POLB (0.71) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6781601 | 0.69 | TP53 (0.64) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL394667 | 0.68 | TSHR (0.57) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL29697071 | 0.68 | TSHR (0.57) | ALDH1A1TP53MEN1KMT2AL3MBTL1 | |
| SCHEMBL16211493 | 0.67 | ALDH1A1 (0.62) | ALDH1A1TP53MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995044-A | Pyridine carboxylic acid amides for mycobacterium infections | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |