SCHEMBL118299

SCHEMBL118299

CC(C)CCCOCC(O)CO

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.60
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PLA2G2C Q5R387 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
LPAR5 Q9H1C0 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 2/20 0.34
AGTR1 P30556 1/20 0.34
SPHK1 Q9NYA1 1/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12632997 0.93 USP2 (0.53) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL12633737 0.93 USP2 (0.53) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL28398602 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL1505222 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL186687 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL25200006 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL116776 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL11196687 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL10596495 0.92 USP2 (0.67) USP2HTTHSD17B10PLA2G2CCYP1A2
SCHEMBL9352436 0.90 USP2 (0.65) USP2HTTHSD17B10PLA2G2CCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320863-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2018-05-16 EP claimed
EP-2320855-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2017-12-27 EP claimed
US-20170258701-A1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2017-09-14 US claimed
US-20170112739-A1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2017-04-27 US claimed
EP-2320862-B1 CLEANSING COMPOSITION KAO GERMANY GMBH (DE) 2016-04-27 EP claimed
EP-2320856-B1 CONDITIONING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2015-11-11 EP claimed
US-8545827-B2 Conditioning composition for hair KAO GERMANY GMBH (DE) 2013-10-01 US claimed
US-8410037-B2 Conditioning composition for hair comprising an alkyl glyceryl ether and quaternized silicone KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2013-04-02 US claimed
US-20110165106-A1 CLEANSING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GBMH (DE) 2011-07-07 US claimed
US-20110165104-A1 CLEANSING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2011-07-07 US claimed
EP-2320856-A1 CONDITIONING COMPOSITION FOR HAIR KPSS-Kao Professional Salon Services GmbH (DE) 2011-05-18 EP claimed
EP-2320863-A1 CLEANSING COMPOSITION KPSS-Kao Professional Salon Services GmbH (DE) 2011-05-18 EP claimed
WO-2010025897-A1 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO claimed
WO-2010025896-A1 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO claimed
WO-2010025895-A1 CLEANSING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO claimed
WO-2010025898-A1 CLEANSING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO claimed
EP-2161015-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP claimed
EP-2161014-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP claimed
EP-2161017-A1 Cleansing composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP claimed
EP-2161018-A1 Cleansing composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258701-A1 CLEANSING COMPOSITION DSG1, DEGS1, SEPTIN7 USP2 2429/4885HTT 643/4885HSD17B10 1247/4885
US-20110165106-A1 CLEANSING COMPOSITION KRT18, DSG1, KCNH3 USP2 1554/4885HTT 2012/4885HSD17B10 2809/4885
US-20170112739-A1 CLEANSING COMPOSITION KRT18, DSG1, VCL USP2 1444/4885HTT 1933/4885HSD17B10 2977/4885
US-20110165104-A1 CLEANSING COMPOSITION KRT18, DSG1, KCNH3 USP2 1531/4885HTT 1572/4885HSD17B10 2185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.