Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836674 | 0.86 | LMNA (0.30) | — | |
| SCHEMBL11832098 | 0.83 | — | — | |
| SCHEMBL11844269 | 0.82 | GPR35 (0.30) | GPR35 | |
| SCHEMBL11848319 | 0.82 | GPR35 (0.33) | GPR35 | |
| SCHEMBL11282636 | 0.80 | HTT (0.38) | ALDH1A1 | |
| SCHEMBL11832947 | 0.80 | — | — | |
| SCHEMBL11843395 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL11845560 | 0.79 | GPR35 (0.30) | GPR35 | |
| SCHEMBL11851354 | 0.77 | — | — | |
| SCHEMBL11843523 | 0.77 | MEN1 (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959488-A | 1-Substituted biguanides for treating hyperacidity or ulceration | WILLIAM H. RORER, INC. (US) | 1976-05-25 | — | — | US | disclosed |