Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829558 | 0.85 | GAA (0.50) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11830959 | 0.80 | MEN1 (0.47) | ALDH1A1POLBMAPTGAAATM | |
| SCHEMBL6009091 | 0.79 | KDM4E (0.55) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL6009094 | 0.79 | KDM4E (0.55) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL18870066 | 0.79 | HPGD (0.55) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL28181525 | 0.78 | HPGD (0.58) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL2049574 | 0.76 | HPGD (0.59) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL27313951 | 0.76 | TAAR1 (0.54) | HPGDRAB9ACYP3A4CYP2C19LMNA | |
| SCHEMBL5988113 | 0.76 | TAAR1 (0.54) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7857 | 0.76 | TAAR1 (0.54) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992396-A | TRANQUILIZERS, HYPNOTICS | SANDOZ, INC. (US) | 1976-11-16 | — | — | US | disclosed |