Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362441 | 0.84 | LMNA (0.62) | HPGDATMSLC6A3POLBL3MBTL1 | |
| SCHEMBL28181525 | 0.83 | HPGD (0.58) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL23685635 | 0.83 | ESR1 (0.48) | HPGDRAB9ACYP3A4CYP2C19ATM | |
| SCHEMBL23685639 | 0.83 | ESR1 (0.48) | HPGDRAB9ACYP3A4CYP2C19ATM | |
| SCHEMBL13998890 | 0.83 | HPGD (0.62) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL9538880 | 0.82 | ATM (0.81) | ATMALDH1A1SLC6A3POLBHTT | |
| SCHEMBL1978150 | 0.81 | HPGD (0.56) | HPGDRAB9ACYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8142471 | 0.81 | SLC6A4 (0.57) | HPGDRAB9AALDH1A1SLC6A3POLB | |
| SCHEMBL6336570 | 0.81 | ATM (0.58) | RAB9AATMSLC6A3L3MBTL1NPC1 | |
| SCHEMBL8257597 | 0.81 | ATM (0.58) | RAB9AATMSLC6A3L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079850-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-05-30 | — | — | WO | disclosed |
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |
| US-7795347-B2 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7795347-B2 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-1457512-B1 | Multi-branched polymer, process for producing the same, and applications thereof | MITSUI CHEMICALS INC (JP) | 2008-05-07 | — | — | EP | disclosed |