Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009091 | 1.00 | KDM4E (0.55) | KDM4ERECQLNPSR1ALDH1A1HPGD | |
| SCHEMBL12767905 | 0.84 | POLB (0.56) | KDM4ERECQLALDH1A1HPGDMEN1 | |
| SCHEMBL10144059 | 0.81 | MEN1 (0.65) | RECQLNPSR1ALDH1A1HPGDMEN1 | |
| SCHEMBL14340788 | 0.80 | HCAR2 (0.60) | KDM4ERECQLMEN1KMT2ALMNA | |
| SCHEMBL11830170 | 0.79 | HPGD (0.51) | ALDH1A1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL6781577 | 0.77 | KMT2A (0.58) | KDM4ERECQLHPGDMEN1KMT2A | |
| SCHEMBL18870066 | 0.76 | HPGD (0.55) | ALDH1A1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL3358264 | 0.76 | ALDH1A1 (0.62) | KDM4ERECQLALDH1A1HPGDMEN1 | |
| SCHEMBL28181525 | 0.76 | HPGD (0.58) | ALDH1A1HPGDCYP3A4CYP2C19RAB9A | |
| SCHEMBL14349698 | 0.75 | HCAR2 (0.60) | KDM4ERECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696898-A2 | ZN 24 -CHELATING MOTIF-TETHERED SHORT-CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-06 | — | — | EP | claimed |
| WO-2005055928-A2 | ZN2+ -CHELATING MOTIF-TETHERED SHORT -CHAIN FATTY ACIDS AS A NOVEL CLASS OF HISTONE DEACETYLASE INHIBITORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-06-23 | — | — | WO | claimed |