Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435391 | 1.00 | AGXT (0.58) | AGXTHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL114254 | 0.85 | AGXT (0.57) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL29519635 | 0.85 | AGXT (0.57) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL7973999 | 0.81 | LMNA (0.63) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL22849632 | 0.81 | AGXT (0.53) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL29550893 | 0.81 | AGXT (0.53) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL29670114 | 0.81 | LMNA (0.63) | AGXTKDM4EMAPK1TDP1RAB9A | |
| SCHEMBL28863401 | 0.80 | ALDH1A1 (0.51) | KDM4ERAB9ANPC1 | |
| SCHEMBL9053577 | 0.80 | SCN4A (0.57) | HTR2AHTR2BMAPK1CYP1A2 | |
| SCHEMBL22838174 | 0.80 | CYP1A2 (0.52) | AGXTKDM4EMAPK1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992384-A | NON-ESTROGENIC ANTIFERTILITY AGENTS | SANDOZ, INC. (US) | 1976-11-16 | — | — | US | disclosed |