Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57323 | 0.82 | HRH3 (0.64) | MAPTALDH1A1CYP3A4TDP1TSHR | |
| Hydrochloric Acid SCHEMBL56245 | 0.80 | HRH3 (0.61) | MAPTALDH1A1CYP3A4TDP1TSHR | |
| Hydrochloric Acid SCHEMBL1322204 | 0.80 | HRH3 (0.61) | MAPTALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL18773885 | 0.80 | AOC3 (0.62) | AOC3ALDH1A1TDP1TSHRHRH3 | |
| SCHEMBL15597723 | 0.78 | AOC3 (0.63) | AOC3ALDH1A1TDP1LOXL2 | |
| SCHEMBL13769273 | 0.78 | AOC3 (0.63) | AOC3ALDH1A1TSHRHRH3 | |
| SCHEMBL6895864 | 0.78 | MAPT (0.48) | AOC3MAPTALDH1A1CYP3A4TDP1 | |
| SCHEMBL18598042 | 0.78 | AOC3 (0.60) | AOC3ALDH1A1TSHRHRH3MAOB | |
| SCHEMBL1793814 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1CYP3A4TSHRMAOB | |
| SCHEMBL1164941 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1CYP3A4TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966706-A | 2,6-Dihydroxy-3-cyano-4-methylpyridine containing azo dyes which contain a functional amino group | CIBA-GEIGY AG (CH) | 1976-06-29 | — | — | US | disclosed |