SCHEMBL57323

SCHEMBL57323

CN(C)Cc1ccc(N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.64
ALDH1A1 P00352 3/20 0.56
TSHR P16473 2/20 0.56
TAAR1 Q96RJ0 2/20 0.54
MAPT P10636 2/20 0.52
CYP3A4 P08684 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
GFER P55789 1/20 0.50
NOS3 P29474 1/20 0.50
NOS1 P29475 1/20 0.50
NOS2 P35228 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
TP53 P04637 1/20 0.46
ALOX15 P16050 1/20 0.46
MAPK1 P28482 1/20 0.46
TTK P33981 1/20 0.44
AURKB Q96GD4 1/20 0.44
INCENP Q9NQS7 1/20 0.44
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL56245 0.97 HRH3 (0.61) HRH3ALDH1A1TSHRTAAR1MAPT
Hydrochloric Acid SCHEMBL1322204 0.97 HRH3 (0.61) HRH3ALDH1A1TSHRTAAR1MAPT
SCHEMBL4728405 0.93 HRH3 (0.77) HRH3ALDH1A1TSHRTAAR1MAPT
SCHEMBL659509 0.86 HRH3 (0.82) HRH3ALDH1A1TSHRTAAR1NOS3
SCHEMBL27532122 0.82 TAAR1 (0.65) HRH3ALDH1A1TSHRTAAR1MAOB
SCHEMBL11831735 0.82 AOC3 (0.62) HRH3ALDH1A1TSHRMAPTCYP3A4
SCHEMBL4277824 0.80 HRH3 (0.58) HRH3ALDH1A1TSHRTAAR1TDP1
SCHEMBL6895864 0.80 MAPT (0.48) HRH3ALDH1A1TSHRMAPTCYP3A4
SCHEMBL3153586 0.80 MAPT (0.48) HRH3ALDH1A1TSHRMAPTCYP3A4
SCHEMBL3972958 0.79 HRH3 (0.64) HRH3ALDH1A1TSHRTAAR1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080401-A Tertiary PTAA copolymer and preparation method thereof 2026-05-26 CN claimed
CN-118703186-B Nano imbibition oil displacement agent for improving recovery ratio 东营江源化工有限公司 2024-11-15 CN claimed
CN-118703186-A Nano imbibition oil displacement agent for improving recovery ratio 东营江源化工有限公司 2024-09-27 CN claimed
US-20160243059-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS UNIST ACADEMY-INDUSTRY RESEARCH CORPORATION (KR) 2016-08-25 US claimed
WO-2014009318-A1 3-{3-[1 -(4-DIMETHYLAMINOMETHYL-PHENYLAMINO)-1 -PHENYL-METH-(Z)-YLIDENE]-2-OXO-2,3-DIHYDRO-1 H-INDOL-6-YLL-PROPYNOIC ACID ETHYLAMIDE AND ITS USE IN THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-01-16 WO claimed
US-20140018372-A1 CRYSTALLINE FORM OF A INDOLINONE DERIVATIVE AND ITS USE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-01-16 US claimed
US-8354444-B2 Substituted pyrrolidine-2-carboxamides HOFFMANN-LA ROCHE INC. (US) 2013-01-15 US claimed
EP-2534132-A1 SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES F. Hoffmann-La Roche AG (CH) 2012-12-19 EP claimed
US-20100152190-A1 Substituted Pyrrolidine-2-Carboxamides F. HOFFMANN-LA ROCHE AG (CH) 2010-06-17 US claimed
US-20080108611-A1 SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-05-08 US claimed
WO-2007084815-A2 SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-07-26 WO claimed
CN-122080401-A Tertiary PTAA copolymer and preparation method thereof 2026-05-26 CN disclosed
EP-4667461-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON S AND GAUCHER DISEASE Children's Hospital Medical Center (US) 2025-12-24 EP disclosed
US-20250382274-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S AND GAUCHER DISEASE CHILDRENS HOSPITAL MED CT (US) 2025-12-18 US disclosed
EP-4067354-B1 NOVEL TRIAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME DAEWOONG PHARMACEUTICAL CO LTD (KR) 2025-10-22 EP disclosed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US disclosed
US-4193800-A COLOR DIFFUSION TRANSFER, POLYMER HAVING ACRYLOLAMINOPHENYL AMMONIUM UNITS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-18 US disclosed
US-4032532-A AZO DYES SANDOZ LTD. (CH) 1977-06-28 US disclosed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US disclosed
US-3966706-A 2,6-Dihydroxy-3-cyano-4-methylpyridine containing azo dyes which contain a functional amino group CIBA-GEIGY AG (CH) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152190-A1 Substituted Pyrrolidine-2-Carboxamides ARG2, CCNY, PYCR1 HRH3 270/4885ALDH1A1 2027/4885TSHR 846/4885
US-20250382274-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S AND GAUCHER DISEASE GBA1, GAA, GBA2 HRH3 2598/4885ALDH1A1 1073/4885TSHR 4231/4885
US-20140018372-A1 CRYSTALLINE FORM OF A INDOLINONE DERIVATIVE AND ITS USE PIR, IDO1, UACA HRH3 2607/4885ALDH1A1 283/4885TSHR 2818/4885
US-20080108611-A1 SUBSTITUTED THIENOPYRIMIDINE KINASE INHIBITORS MAP4K2, MAP3K6, MAP3K2 HRH3 1921/4885ALDH1A1 1988/4885TSHR 2375/4885
US-20160243059-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS APP, PSEN1, BACE1 HRH3 3635/4885ALDH1A1 1006/4885TSHR 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.