Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159482 | 0.84 | CA2 (0.44) | CA2CA9PTPN1PTPN2PTPN11 | |
| SCHEMBL28804125 | 0.80 | CA9 (0.46) | CA2CA9CA1TDP1ALDH1A1 | |
| SCHEMBL17157443 | 0.79 | CA2 (0.42) | CA2CA9PTPN1PTPN2PTPN11 | |
| SCHEMBL11832186 | 0.77 | PTPN1 (0.40) | PTPN1PTPN2PTPN11TDP1ALDH1A1 | |
| SCHEMBL17157444 | 0.76 | TDP1 (0.42) | CA2CA9PTPN1PTPN2PTPN11 | |
| SCHEMBL31069158 | 0.76 | CA2 (0.59) | CA2CA9PTPN1PTPN2PTPN11 | |
| SCHEMBL1617207 | 0.76 | CA2 (0.50) | CA2CA9CA1TDP1ALDH1A1 | |
| SCHEMBL781003 | 0.76 | CA2 (0.47) | CA2CA9CA1KMT2A | |
| SCHEMBL778120 | 0.75 | CA2 (0.61) | CA2CA9CA1ALDH1A1KMT2A | |
| SCHEMBL29159480 | 0.75 | CA2 (0.43) | CA2CA9CA1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992333-A | NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER | ROHM AND HAAS COMPANY (US) | 1976-11-16 | — | — | US | disclosed |