Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 8/20 | 0.40 |
| ▸ | CA1 known ✓ | P00915 | 6/20 | 0.35 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17157443 | 0.79 | CA2 (0.42) | TDP1CA2CA9ALDH1A1CA1 | |
| SCHEMBL9861431 | 0.77 | CA2 (0.46) | CA2CA9CA1KMT2ACA12 | |
| SCHEMBL7406291 | 0.77 | KMT2A (0.49) | CA2CA9ALDH1A1CA1KMT2A | |
| SCHEMBL9860983 | 0.77 | CA2 (0.59) | CA2CA9ALDH1A1CA1KMT2A | |
| SCHEMBL29159482 | 0.77 | CA2 (0.44) | TDP1CA2CA9ALDH1A1CA1 | |
| SCHEMBL2932534 | 0.77 | CA2 (0.57) | TDP1CA2CA9ALDH1A1CA1 | |
| SCHEMBL19923105 | 0.76 | CA2 (0.41) | TDP1CA2CA9ALDH1A1CA1 | |
| SCHEMBL11832180 | 0.76 | CA2 (0.42) | TDP1CA2CA9ALDH1A1CA1 | |
| SCHEMBL9861698 | 0.75 | IDO1 (0.47) | CA2CA9CA1KMT2ACA12 | |
| SCHEMBL9861721 | 0.74 | KMT2A (0.49) | CA2CA9ALDH1A1CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10374178-B2 | Method for making devices having dielectric layers with thiosulfate-containing polymers | EASTMAN KODAK COMPANY (US) | 2019-08-06 | — | — | US | disclosed |
| EP-3155623-B1 | DEVICES HAVING DIELECTRIC LAYERS WITH THIOSULFATE-CONTAINING POLYMERS | EASTMAN KODAK CO (US) | 2019-05-08 | — | — | EP | disclosed |
| US-20170222167-A1 | METHOD FOR MAKING DEVICES HAVING DIELECTRIC LAYERS WITH THIOSULFATE-CONTAINING POLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2017-08-03 | — | — | US | disclosed |
| US-9709889-B2 | Forming conductive metal patterns using thiosulfate copolymers | EASTMAN KODAK COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9691997-B2 | Devices having dielectric layers with thiosulfate-containing polymers | EASTMAN KODAK COMPANY (US) | 2017-06-27 | — | — | US | disclosed |
| US-9653694-B2 | Precursor dielectric composition with thiosulfate-containing polymers | EASTMAN KODAK COMPANY (US) | 2017-05-16 | — | — | US | disclosed |
| US-9637581-B2 | Thiosulfate-containing polymers associated with photosensitizer component | EASTMAN KODAK COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| US-9453095-B2 | Photocurable and thermally curable thiosulfate-containing polymers | EASTMAN KODAK COMPANY (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160147148-A1 | FORMING CONDUCTIVE METAL PATTERNS USING THIOSULFATE COPOLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2016-05-26 | — | — | US | disclosed |
| US-9329482-B2 | Forming conductive metal patterns using thiosulfate copolymers | EASTMAN KODAK COMPANY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150364688-A1 | PRECURSOR DIELECTRIC COMPOSITION WITH THIOSULFATE-CONTAINING POLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2015-12-17 | — | — | US | disclosed |
| US-20150364687-A1 | DEVICES HAVING DIELECTRIC LAYERS WITH THIOSULFATE-CONTAINING POLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2015-12-17 | — | — | US | disclosed |
| US-20150361201-A1 | PHOTOCURABLE AND THERMALLY CURABLE THIOSULFATE-CONTAINING POLYMERS | BANK OF AMERICA, N.A., AS AGENT | 2015-12-17 | — | — | US | disclosed |
| US-20150361206-A1 | THIOSULFATE-CONTAINING POLYMERS ASSOCIATED WITH PHOTOSENSITIZER COMPONENT | BANK OF AMERICA, N.A., AS AGENT | 2015-12-17 | — | — | US | disclosed |
| US-20150293451-A1 | FORMING CONDUCTIVE METAL PATTERNS USING THIOSULFATE COPOLYMERS | BANK OF AMERICA, N.A. | 2015-10-15 | — | — | US | disclosed |