Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646830 | 0.85 | KDM4E (0.49) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL27722503 | 0.82 | KDM4E (0.53) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL5248068 | 0.81 | KDM4E (0.51) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL2647186 | 0.81 | KDM4E (0.51) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL18680739 | 0.81 | ALDH1A1 (0.54) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL27870807 | 0.81 | KDM4E (0.55) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL11449929 | 0.79 | KIF11 (0.57) | KDM4EGAAALDH1A1POLBATM | |
| SCHEMBL3646958 | 0.78 | KDM4E (0.49) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL12879674 | 0.78 | GAA (0.52) | KDM4EGAAALDH1A1POLBMAPT | |
| SCHEMBL10800363 | 0.78 | TSHR (0.48) | KDM4EGAAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981886-A | Amino-benzimidazole derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |