Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | CEL | P19835 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837224 | 0.87 | THRB (0.43) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11834848 | 0.85 | THRB (0.41) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11827805 | 0.85 | THRB (0.41) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11833594 | 0.85 | THRB (0.40) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11828906 | 0.85 | THRB (0.41) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11842594 | 0.85 | PTGDR2 (0.40) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11828369 | 0.85 | CYP2C9 (0.44) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11833673 | 0.85 | SLC6A3 (0.45) | THRBPTGDR2PTGDRPTGER2NSD2 | |
| SCHEMBL11831779 | 0.84 | THRB (0.46) | THRBPTGDR2PTGDRBCL2L1MCL1 | |
| SCHEMBL11833933 | 0.84 | THRB (0.41) | THRBPTGDR2PTGDRPTGER2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985788-A | Phenyl propionic acids and derivatives thereof | WILLIAM H. RORER, INC. (US) | 1976-10-12 | — | — | US | disclosed |