Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19816797 | 0.79 | MAPT (0.30) | MAPT | |
| SCHEMBL11845653 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL10792327 | 0.75 | MAPT (0.39) | MAPTKDM4ELMNACYP2C19ALDH1A1 | |
| SCHEMBL10204415 | 0.74 | — | — | |
| SCHEMBL27672693 | 0.74 | — | — | |
| SCHEMBL2690863 | 0.73 | — | — | |
| SCHEMBL27781831 | 0.73 | ALDH1A1 (0.42) | MAPTKDM4ELMNAALDH1A1ALOX15 | |
| SCHEMBL4868570 | 0.73 | ALDH1A1 (0.42) | MAPTKDM4ELMNAALDH1A1ALOX15 | |
| SCHEMBL24862 | 0.73 | ALDH1A1 (0.42) | MAPTKDM4ELMNAALDH1A1ALOX15 | |
| SCHEMBL11484280 | 0.71 | L3MBTL1 (0.40) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954984-A | ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |