Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824353 | 1.00 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11823605 | 0.86 | MAPT (0.40) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11835079 | 0.86 | ALDH1A1 (0.54) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11823359 | 0.86 | ALDH1A1 (0.54) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11821217 | 0.86 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11819383 | 0.83 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11825507 | 0.83 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11819074 | 0.82 | LMNA (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11824142 | 0.81 | MAPT (0.38) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11821518 | 0.81 | MAPT (0.39) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |