Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835124 | 1.00 | LMNA (0.56) | LMNAALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL11834237 | 0.86 | GRIN2D (0.50) | LMNAALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL11834231 | 0.86 | GRIN2D (0.50) | LMNAALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL7320187 | 0.78 | NPC1 (0.52) | ALDH1A1MGLLMEN1KMT2ATSHR | |
| SCHEMBL7320175 | 0.78 | NPC1 (0.52) | ALDH1A1MGLLMEN1KMT2ATSHR | |
| SCHEMBL967320 | 0.78 | LMNA (0.70) | LMNAALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL1794953 | 0.78 | GRIN2D (0.74) | LMNAALDH1A1MGLLTSHRMAPK1 | |
| SCHEMBL1794951 | 0.78 | GRIN2D (0.74) | LMNAALDH1A1MGLLTSHRMAPK1 | |
| SCHEMBL21603953 | 0.78 | MGLL (0.66) | LMNAALDH1A1MGLLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9555748 | 0.76 | NPC1 (0.50) | ALDH1A1MGLLMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954995-A | Mono-and disubstituted hydroxyguanidines in the treatment of depression | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-04 | — | — | US | claimed |