Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.53 |
| ▸ | PTPRC | P08575 | 3/20 | 0.53 |
| ▸ | PTPRB | P23467 | 3/20 | 0.53 |
| ▸ | PTPRE | P23469 | 3/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.53 |
| ▸ | PTPRF | P10586 | 2/20 | 0.49 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988900 | 0.88 | GPR35 (0.56) | GPR35LPAR2LPAR3PTPN1PTPN2 | |
| SCHEMBL7974559 | 0.87 | KDM4E (0.57) | GPR35LPAR2LPAR3PTPN1PTPN2 | |
| SCHEMBL7988973 | 0.87 | GPR35 (0.65) | GPR35LPAR2LPAR3PTPN1PTPN2 | |
| SCHEMBL7988047 | 0.82 | GPR35 (0.46) | GPR35LPAR2LPAR3PTPN1PTPN2 | |
| SCHEMBL5697299 | 0.81 | GPR35 (0.68) | GPR35PTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL7984836 | 0.79 | NPC1 (0.50) | GPR35NPC1RAB9A | |
| SCHEMBL11395900 | 0.78 | GPR35 (1.00) | GPR35PTPN1PTPN2PTPRFPTPRA | |
| SCHEMBL7988976 | 0.78 | GPR35 (0.42) | GPR35LPAR2LPAR3PTPN1PTPN2 | |
| SCHEMBL4315667 | 0.77 | PTPN1 (0.64) | GPR35PTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL30583240 | 0.77 | PTPN1 (0.64) | GPR35PTPN1PTPN2PTPRCPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962308-A | Process for converting esters to amine salts | THE UPJOHN COMPANY (US) | 1976-06-08 | — | — | US | disclosed |