Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11846087 | 0.99 | KDM4E (0.61) | KDM4EMAPTLMNAGPR35KMT2A | |
| SCHEMBL11836348 | 0.86 | KDM4E (0.65) | KDM4EMAPTLMNAGPR35KMT2A | |
| SCHEMBL11834520 | 0.85 | KMT2A (0.46) | KDM4EMAPTLMNAGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11828807 | 0.85 | KDM4E (0.64) | KDM4EMAPTLMNAGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11843962 | 0.84 | KMT2A (0.45) | KDM4EMAPTLMNAGPR35KMT2A | |
| SCHEMBL11842018 | 0.84 | KDM4E (0.69) | KDM4EMAPTLMNAGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11837379 | 0.83 | KDM4E (0.67) | KDM4EMAPTLMNAGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11837405 | 0.82 | KMT2A (0.61) | KDM4EMAPTLMNAGPR35KMT2A | |
| SCHEMBL11832922 | 0.78 | KDM4E (0.72) | KDM4EMAPTLMNAGPR35KMT2A | |
| SCHEMBL11839505 | 0.78 | KDM4E (0.58) | KDM4EMAPTLMNAGPR35KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |