Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11847290 | 0.99 | KDM4E (0.57) | KDM4ELMNAMAPTGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11832562 | 0.87 | KDM4E (0.55) | KDM4ELMNAMAPTGPR35KMT2A | |
| SCHEMBL11835472 | 0.78 | KDM4E (0.62) | KDM4ELMNAMAPTGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11846087 | 0.77 | KDM4E (0.61) | KDM4ELMNAMAPTGPR35KMT2A | |
| SCHEMBL11836348 | 0.75 | KDM4E (0.65) | KDM4ELMNAMAPTGPR35KMT2A | |
| SCHEMBL11837546 | 0.74 | KDM4E (0.61) | KDM4ELMNAMAPTGPR35KMT2A | |
| SCHEMBL11832922 | 0.74 | KDM4E (0.72) | KDM4ELMNAMAPTGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11828807 | 0.74 | KDM4E (0.64) | KDM4ELMNAMAPTGPR35KMT2A | |
| Hydrochloric Acid SCHEMBL11837543 | 0.73 | KDM4E (0.70) | KDM4ELMNAMAPTGPR35KMT2A | |
| SCHEMBL11839509 | 0.72 | KDM4C (0.54) | KDM4ELMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |
| JP-51125281-A | — | — | None | — | — | JP | disclosed |
| JP-S51125281-A | A PROCESS FOR PREPARING INDAZOLE DERIVATIVES | CHUGAI PHARMACEUT CO LTD | 1976-11-01 | — | — | JP | disclosed |