Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11846094 | 0.99 | MAPT (0.58) | MAPTKDM4EMAT2AADRA1AHRH1 | |
| SCHEMBL11842021 | 0.93 | MAPT (0.57) | MAPTKDM4EMAT2AADRA1AHRH1 | |
| Hydrochloric Acid SCHEMBL11837384 | 0.91 | MAPT (0.56) | MAPTKDM4EMAT2AADRA1AHRH1 | |
| SCHEMBL11836353 | 0.88 | MAPT (0.57) | MAPTKDM4EMAT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11828812 | 0.86 | MAPT (0.56) | MAPTKDM4EMAT2ALMNAALDH1A1 | |
| SCHEMBL11834527 | 0.86 | KDM4E (0.43) | MAPTKDM4ELMNAALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11843968 | 0.85 | KDM4E (0.42) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL11836098 | 0.84 | KDM4E (0.58) | KDM4EADRA1ALMNAALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11837410 | 0.82 | KDM4E (0.57) | KDM4EADRA1ALMNAALDH1A1TSHR | |
| SCHEMBL11832928 | 0.81 | MAPT (0.57) | MAPTKDM4ELMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |