Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11828812 | 0.99 | MAPT (0.56) | MAPTKDM4ERAD52KMT2AMEN1 | |
| SCHEMBL11835478 | 0.88 | MAPT (0.59) | MAPTKDM4EKMT2AMEN1TSHR | |
| SCHEMBL11834839 | 0.86 | POLB (0.43) | MAPTKDM4ERAD52KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11846094 | 0.86 | MAPT (0.58) | MAPTKDM4EKMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL11833169 | 0.85 | PKM (0.42) | MAPTKDM4ERAD52KMT2AMEN1 | |
| SCHEMBL11837490 | 0.84 | HSD17B10 (0.56) | KDM4ERAD52KMT2ATSHRPOLB | |
| Hydrochloric Acid SCHEMBL11835277 | 0.83 | HSD17B10 (0.54) | KDM4ERAD52KMT2ATSHRPOLB | |
| SCHEMBL11842021 | 0.83 | MAPT (0.57) | MAPTKDM4EKMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL11837384 | 0.82 | MAPT (0.56) | MAPTKDM4EKMT2AMEN1TSHR | |
| SCHEMBL11835521 | 0.80 | HSD17B10 (0.45) | MAPTKDM4EKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |