SCHEMBL1183571

SCHEMBL1183571

CC(COC(=O)OCC(C)(c1ccc(O)cc1)c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.53
ESR2 Q92731 9/20 0.53
CYP3A4 P08684 3/20 0.53
ALDH1A1 P00352 3/20 0.53
TSHR P16473 3/20 0.45
ESRRG P62508 2/20 0.45
SLC6A2 P23975 2/20 0.45
LMNA P02545 1/20 0.45
TYR P14679 1/20 0.45
AR P10275 1/20 0.45
HPGD P15428 1/20 0.45
SLC6A4 P31645 1/20 0.45
HTR6 P50406 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CHRM2 P08172 2/20 0.43
SHBG P04278 1/20 0.42
MAPK1 P28482 1/20 0.42
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30862105 0.87 ESR1 (0.56) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL3295655 0.85 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL10790686 0.85 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL10953758 0.84 ESR1 (0.49) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL8003820 0.84 MAPK1 (0.58) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL5232906 0.82 HIF1A (0.47) ESR1ESR2CYP3A4ALDH1A1SLC6A3
SCHEMBL9147586 0.81 ESR1 (0.46) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL5450224 0.81 ESR1 (0.46) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL28517058 0.81 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL8816210 0.81 CYP3A4 (0.46) ESR1ESR2CYP3A4ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332921-B1 Multiactive electrophotographic element EASTMAN KODAK CO (US) 1995-05-10 EP claimed
EP-0626425-A2 Compatible thermoplastic compositions based on polyesters and polycarbonates ENICHEM S.p.A. (IT) 1994-11-30 EP claimed
EP-0332921-A2 Multiactive electrophotographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-09-20 EP claimed
US-4840860-A TRIARYLAMINE CHARGE TRANSPORT MATERIAL IN POLYESTER POLYCARBONATE BINDER BLENDS EASTMAN KODAK COMPANY (US) 1989-06-20 US claimed
US-4840861-A TRIARYLMETHANE CHARGE TRANSPORT MATERIAL IN POLYESTER POLYCARBONATE BINDER BLEND EASTMAN KODAK COMPANY (US) 1989-06-20 US claimed
US-4563516-A PHASE BOUNDARY POLYMERIZATION BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US claimed
US-4141735-A HEAT TEMPERING EASTMAN KODAK COMPANY (US) 1979-02-27 US claimed
US-4097425-A POLYCARBONATES, POLYESTERS, SUBSTITUTED 3,6-DIHYDRO-1,3,4-OXDIAZIN-2-ONE GENERAL ELECTRIC COMPANY (US) 1978-06-27 US claimed
JP-1282558-A None JP disclosed
JP-63268760-A None JP disclosed
JP-1038467-A None JP disclosed
JP-60008356-A None JP disclosed
JP-63207848-A None JP disclosed
JP-61162546-A None JP disclosed
EP-0057897-A2 Process for crosslinking polycarbonate resins THE FURUKAWA ELECTRIC CO., LTD. (JP) 1982-08-18 EP disclosed
US-4316838-A SALT OF AN ETHER SULFONATE TEIJIN CHEMICALS LTD. (JP) 1982-02-23 US disclosed
US-4222910-A SULFURIC ESTER OF AN ALCOHOL OR A METAL SULFONATE COMPOUND TEIJIN CHEMICALS, LTD. (JP) 1980-09-16 US disclosed
US-4211823-A Tintable coatings and articles having such coatings TORAY INDUSTRIES, INC. (JP) 1980-07-08 US disclosed
US-4197384-A Stabilized polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1980-04-08 US disclosed
US-4141735-A HEAT TEMPERING EASTMAN KODAK COMPANY (US) 1979-02-27 US disclosed