SCHEMBL8003820

SCHEMBL8003820

CC(COC(=O)c1ccc(C(=O)OCC(C)(c2ccc(O)cc2)c2ccc(O)cc2)cc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.58
TSHR P16473 3/20 0.58
ESR1 P03372 5/20 0.58
ESR2 Q92731 4/20 0.58
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
ALDH1A1 P00352 3/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
KDR P35968 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881682 0.87 TSHR (0.46) MAPK1TSHRESR1ESR2CA12
SCHEMBL1728720 0.84 MAPK1 (0.64) MAPK1TSHRESR1ESR2CA12
SCHEMBL1183571 0.84 ESR1 (0.53) MAPK1TSHRESR1ESR2CA12
SCHEMBL23484566 0.84 MAPK1 (0.64) MAPK1TSHRESR1ESR2CA12
SCHEMBL18652233 0.84 MAPK1 (0.64) MAPK1TSHRESR1ESR2CA12
SCHEMBL30862105 0.82 ESR1 (0.56) MAPK1TSHRESR1ESR2CA12
SCHEMBL3295655 0.81 ESR1 (0.50) MAPK1TSHRESR1ESR2CA12
SCHEMBL24305987 0.81 MAPK1 (0.60) MAPK1TSHRESR1ESR2CA12
SCHEMBL10790686 0.81 ESR1 (0.54) MAPK1TSHRESR1ESR2CA12
SCHEMBL1348236 0.80 MAPK1 (0.68) MAPK1TSHRESR1ESR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117922-A Solid, storage-stable antistat mixtures and process for their preparation CLARIANT GMBH (DE) 2000-09-12 US disclosed
US-6013706-A Process for the preparation of hyrolysis-stable trivalent phosphorus compounds and their use as stabilizers for thermoplastics CLARIANT GMBH (DE) 2000-01-11 US disclosed
US-5633378-A STABILIZER FOR POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-27 US disclosed
US-5594142-A USING SOLVENT MIXTURE AND BASIC CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
US-5550242-A REACTION CARRIED OUT IN INERT ORGANIC SOLVENT IN PRESENCE OF SOLID ALKALI METAL HYDROXIDE OR A MIXTURE OF HYDROXIDE AND WATER; AVOIDS USE OF PHASE TRANSFER CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
US-5550234-A STABILIZERS WITH VERY LOW VOLATILITY AT ELEVATED TEMPERATURES HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
US-5539040-A Plastics molding composition for production of moldings having a decorative effect HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
US-5356967-A Raeacting formed Grignard reagent with a chloro-dibenzooxa-phosphorine derivative HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5331034-A Deactivation of catalyst residues with ditrimethylolpropane HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
US-5298541-A Molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
US-5281640-A For thermoplastic or thermosetting plastics, polymer-containing polymerized mono- or diolefin molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-25 US disclosed
US-5200446-A PLASTIC MOLDING COMPOUND TREATED WITH AN ANTISTATIC AGENT HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-06 US disclosed
US-5169925-A Light stabilizers for polymers; photooxidation resistance; nondestructive; nondiffusing; heat resistance; molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-08 US disclosed
EP-0299925-B1 PIPERIDINE-TRIAZINE COMPOUNDS FOR USE AS STABILIZERS FOR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1992-12-02 EP disclosed
US-4992493-A Heat, oxidation resistance; photostability CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0299925-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1989-01-18 EP disclosed
US-4692486-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1987-09-08 US disclosed