Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034200 | 0.84 | HIF1A (0.47) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL1183571 | 0.82 | ESR1 (0.53) | KMT2AALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL28833640 | 0.82 | HIF1A (0.42) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL7908308 | 0.80 | LMNA (0.43) | CYP2C19KMT2ACYP2D6CES1TDP1 | |
| SCHEMBL27612149 | 0.80 | HIF1A (0.41) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL4938622 | 0.79 | HIF1A (0.40) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL11266149 | 0.77 | HIF1A (0.44) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL6823582 | 0.77 | CYP2C19 (0.49) | HIF1ACYP2C19ALDH1A1CHRM3MAPK1 | |
| SCHEMBL5906803 | 0.76 | MAPK1 (0.48) | HIF1ACYP2C19MAPTKMT2AKCNN4 | |
| SCHEMBL25336560 | 0.74 | MAPT (0.46) | HIF1ACYP2C19MAPTKMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645422-A1 | Flame retardant polycarbonate blends | GENERAL ELECTRIC COMPANY (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0106096-B1 | POLYCARBONATE RESIN MIXTURES | GENERAL ELECTRIC COMPANY (US) | 1986-12-03 | — | — | EP | claimed |
| US-4537930-A | STRESS CRACK RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 1985-08-27 | — | — | US | claimed |
| EP-0106096-A1 | Polycarbonate resin mixtures | GENERAL ELECTRIC COMPANY (US) | 1984-04-25 | — | — | EP | claimed |
| US-4122131-A | Polyblend composition comprising aromatic polycarbonate, polyolefin, selectively hydrogenated block copolymer and olefinic copolymer | GENERAL ELECTRIC COMPANY (US) | 1978-10-24 | — | — | US | claimed |
| EP-1315692-B1 | 1,1-BIS(4-HYDROXYPHENYL)-3-ALKYLCYCLOHEXANES, METHOD FOR THEIR PREPARATION AND POLYCARBONATES PREPARED THEREFROM | GEN ELECTRIC (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20070191527-A1 | POLYMER EXFOLIATED PHYLLOSILICATE NANOCOMPOSITE COMPOSITIONS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-08-16 | — | — | US | disclosed |
| WO-2003089516-A1 | MISCIBLE BLENDS OF POLYESTERS AND POLYCARBONATES WITH GOOD THERMAL CHARACTERISTICS, AND RELATED PROCESSES AND ARTICLES | GENERAL ELECTRIC COMPANY (US) | 2003-10-30 | — | — | WO | disclosed |
| US-20030195295-A1 | Miscible blends of polyesters and polycarbonates with good thermal characteristics, and related processes and articles | GENERAL ELECTRIC COMPANY | 2003-10-16 | — | — | US | disclosed |
| EP-1315692-A1 | 1,1-BIS(4-HYDROXYPHENYL)-3-ALKYLCYCLOHEXANES, METHOD FOR THEIR PREPARATION AND POLYCARBONATES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6498271-B2 | BIOTRANSFORMATION OF AN OLEFINIC MONOCARBOXYLIC ACID (OLEIC ACID) TO THE 1,18-OCTADEC-9-ENEDIOIC ACID IN PRESENCE OF CANDIDA TROPICALIS, A YEAST STRAIN, FOLLOWED BY CARBOXYLATON OF INTERMEDIATE BY REACTION WITH CARBON MONOXIDE AND WATER | GENERAL ELECTRIC COMPANY | 2002-12-24 | — | — | US | disclosed |
| US-20020169339-A1 | Tricarboxylic acids, method, and branched polycarbonates prepared therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-11-14 | — | — | US | disclosed |
| US-5300622-A | Ductile; high glass transition temperature | GENERAL ELECTRIC COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| US-5281688-A | Polycarbonate from 1,3-bis(4-hydroxyphenyl)-1,3-dialkylcyclohexanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5281689-A | Polycarbonate from bis[4'-(4-hydroxyphenyl)-phenyl]alkanes | GENERAL ELECTRIC COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0106096-B1 | POLYCARBONATE RESIN MIXTURES | GENERAL ELECTRIC COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4537930-A | STRESS CRACK RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4424254-A | Metal-thermoplastic-metal laminates | MONSANTO COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4369222-A | Metal-thermoplastic-metal laminates | MONSANTO COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0013146-B1 | METAL-THERMOPLASTIC-METAL LAMINATES AND A PROCESS FOR THE PREPARATION OF SUCH LAMINATES | MONSANTO COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169339-A1 | Tricarboxylic acids, method, and branched polycarbonates prepared therefrom | HADHB, HADHA, NOTUM | HIF1A 1740/4885CYP2C19 191/4885MAPT 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.