Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828886 | 0.94 | LMNA (0.49) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL8387215 | 0.88 | AKR1C3 (0.46) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11836179 | 0.88 | AKR1C3 (0.44) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11835464 | 0.88 | AKR1C3 (0.53) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11840552 | 0.88 | AKR1C3 (0.45) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11843204 | 0.86 | AKR1C3 (0.45) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11835245 | 0.86 | AKR1C3 (0.45) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11837148 | 0.86 | AKR1C3 (0.49) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11828964 | 0.85 | AKR1C3 (0.48) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL13011086 | 0.85 | PTGDR2 (0.45) | MEN1KMT2AALOX15TSHRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | claimed |
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | disclosed |