Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 8/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 4/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823662 | 0.86 | MMP12 (0.58) | MMEACE | |
| SCHEMBL11824539 | 0.85 | PPARG (0.49) | MAOBMME | |
| Hydrochloric Acid SCHEMBL1912603 | 0.83 | MAOB (0.58) | MAOBTAAR1MMEACEHCAR2 | |
| SCHEMBL9392693 | 0.83 | KMT2A (0.50) | TAAR1 | |
| SCHEMBL11836653 | 0.81 | PTGER4 (0.49) | — | |
| SCHEMBL9492547 | 0.80 | PPARG (0.51) | TAAR1 | |
| SCHEMBL4201881 | 0.79 | ABCC4 (0.67) | MAOBTAAR1MMEACEMMEL1 | |
| SCHEMBL11918359 | 0.78 | MME (0.67) | MAOBTAAR1MMEACEMMEL1 | |
| SCHEMBL6903404 | 0.78 | MME (0.67) | MAOBTAAR1MMEACEMMEL1 | |
| SCHEMBL11830344 | 0.77 | MME (0.49) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |