Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824543 | 0.85 | KMT2A (0.47) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL11836649 | 0.81 | MAOB (0.55) | — | |
| SCHEMBL9890642 | 0.80 | CHRM1 (0.57) | PTGER4PTGER3PTGER1PTGER2CHRM1 | |
| SCHEMBL11833616 | 0.79 | DPP4 (0.46) | KMT2A | |
| SCHEMBL9392693 | 0.78 | KMT2A (0.50) | KMT2A | |
| SCHEMBL11827466 | 0.76 | CHRM1 (0.48) | PTGER4PTGER3PTGER1PTGER2CHRM1 | |
| SCHEMBL11830344 | 0.74 | MME (0.49) | DCLRE1B | |
| SCHEMBL28303450 | 0.73 | KMT2A (0.68) | PTGER4PTGER3PTGER1PTGER2KMT2A | |
| SCHEMBL9289984 | 0.73 | CHRM1 (0.49) | PTGER4PTGER3PTGER1PTGER2CHRM1 | |
| SCHEMBL2393760 | 0.73 | CHRM1 (0.56) | PTGER4PTGER3PTGER1PTGER2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |