Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834832 | 0.94 | RAB9A (0.56) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11832770 | 0.91 | KMT2A (0.57) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11832824 | 0.85 | KMT2A (0.61) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11824796 | 0.84 | KMT2A (0.54) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11839070 | 0.83 | KMT2A (0.57) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11832585 | 0.81 | MEN1 (0.68) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11773712 | 0.79 | LMNA (0.48) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL11827890 | 0.77 | KMT2A (0.58) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11831710 | 0.77 | KMT2A (0.50) | KMT2AMEN1GAAPKMRAB9A | |
| SCHEMBL11827269 | 0.76 | MEN1 (0.63) | KMT2AMEN1GAAPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |