Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | YAP1 | P46937 | 2/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15336652 | 0.86 | — | — | |
| SCHEMBL11838557 | 0.82 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2HTTPOLB | |
| SCHEMBL8904075 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2HTTPOLB | |
| SCHEMBL16083079 | 0.81 | — | — | |
| SCHEMBL1150560 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTNPC1 | |
| SCHEMBL12862009 | 0.80 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTNPC1 | |
| SCHEMBL15998838 | 0.78 | CHRNB2 (0.59) | ALDH1A1LMNASMN1; SMN2POLBCHRNB2 | |
| SCHEMBL16082804 | 0.78 | — | — | |
| SCHEMBL16472339 | 0.78 | CHRNB2 (0.59) | ALDH1A1LMNASMN1; SMN2POLBCHRNB2 | |
| SCHEMBL11841192 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998808-A | INSECTICIDES, FUNGICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |