Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.46 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.42 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824214 | 0.74 | LMNA (0.50) | MMEACEACE2GAAABCC4 | |
| SCHEMBL30901114 | 0.74 | TAAR1 (0.47) | GAAABCC4LMNATSHRPTGS1 | |
| SCHEMBL13889581 | 0.73 | ESR1 (0.54) | GAAABCC4LMNATSHRPTGS1 | |
| SCHEMBL11837950 | 0.73 | PTGS2 (0.54) | PTGS2GAACYP1A2CYP2C9PKM | |
| SCHEMBL5171029 | 0.73 | ABCC4 (0.52) | MMEACEACE2GAAABCC4 | |
| SCHEMBL20661665 | 0.73 | ABCC4 (0.52) | MMEACEACE2GAAABCC4 | |
| SCHEMBL11836244 | 0.71 | MME (0.52) | MMEACEACE2CPA1GAA | |
| SCHEMBL6594704 | 0.71 | NPC1 (0.47) | LMNATSHRPTGS1HTTCYP1A2 | |
| SCHEMBL6532058 | 0.70 | BLM (0.69) | MMEACEACE2PTGS2GAA | |
| SCHEMBL14037306 | 0.70 | BLM (0.69) | MMEACEACE2PTGS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |