Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | RAD52 | P43351 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11835277 | 0.99 | HSD17B10 (0.54) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11834839 | 0.85 | POLB (0.43) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11836098 | 0.85 | KDM4E (0.58) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11833169 | 0.84 | PKM (0.42) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11836353 | 0.84 | MAPT (0.57) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11837410 | 0.84 | KDM4E (0.57) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11828812 | 0.83 | MAPT (0.56) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11834589 | 0.80 | KDM4E (0.63) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL17322911 | 0.80 | HSD17B10 (0.64) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11833093 | 0.79 | KDM4E (0.61) | HSD17B10KDM4ETSHRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |