Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 6/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.36 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841233 | 0.75 | TTR (0.55) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11798714 | 0.74 | NPC1 (0.54) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11871046 | 0.72 | TTR (0.60) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11863092 | 0.72 | LTB4R (0.59) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11835904 | 0.71 | NPC1 (0.51) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11552376 | 0.71 | TTR (0.43) | NPC1RAB9ATTRKDM4EALDH1A1 | |
| SCHEMBL11801191 | 0.71 | TTR (0.55) | NPC1RAB9ATTRAKR1B1KDM4E | |
| SCHEMBL11553175 | 0.71 | KDM4E (0.39) | NPC1RAB9ATTRKDM4EALDH1A1 | |
| SCHEMBL11748405 | 0.71 | MAOB (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11871523 | 0.71 | LTB4R (0.60) | NPC1RAB9ATTRAKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |