Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777675 | 0.87 | SIGMAR1 (0.61) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL10252829 | 0.83 | SIGMAR1 (0.58) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL6427482 | 0.81 | SIGMAR1 (0.56) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL15710462 | 0.80 | SIGMAR1 (0.55) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL612153 | 0.80 | SIGMAR1 (0.55) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL18854250 | 0.80 | SIGMAR1 (0.55) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL171980 | 0.79 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL29674557 | 0.79 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL15076889 | 0.79 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1ACFTRGOPC | |
| SCHEMBL3401467 | 0.79 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1ACFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957828-A | 3-Aminoalkyl-1,3-dihydro-3-phenylspiro[isobenzofurans] | AMERICAN HOECHST CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |