Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435586 | 0.83 | CLK4 (0.38) | NPC1RAB9ATP53SMN1; SMN2MAPK1 | |
| SCHEMBL2500804 | 0.79 | KMT2A (0.47) | LMNANPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL28227388 | 0.79 | CLK4 (0.52) | LMNANPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL20746793 | 0.78 | TP53 (0.53) | LMNANPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL10731993 | 0.74 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2TSHRMAPT | |
| SCHEMBL4303322 | 0.74 | MEN1 (0.56) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL17701519 | 0.73 | KIF11 (0.48) | LMNANPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL27668598 | 0.73 | CLK4 (0.66) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL30186716 | 0.73 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPK1ADORA3 | |
| SCHEMBL14656056 | 0.73 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |