Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826120 | 0.85 | LOXL2 (0.51) | LOXL2TP53AGXTMEN1KMT2A | |
| SCHEMBL153830 | 0.83 | LOXL2 (0.46) | LOXL2TP53AGXTMEN1KMT2A | |
| SCHEMBL2867991 | 0.82 | LOXL2 (0.45) | LOXL2TP53AGXTMEN1KMT2A | |
| SCHEMBL14075637 | 0.81 | LOXL2 (0.69) | LOXL2AGXTHTR1AHTR2BKDM4E | |
| SCHEMBL28954987 | 0.80 | LOXL2 (0.46) | LOXL2TP53AGXTHTR1AHTR2B | |
| SCHEMBL10369285 | 0.79 | LOXL2 (0.53) | LOXL2TP53AGXTHTR1AHTR2B | |
| SCHEMBL11107879 | 0.77 | LOXL2 (0.55) | LOXL2TP53AGXTNPC1HTR1A | |
| SCHEMBL11671781 | 0.76 | HTR2B (0.65) | LOXL2AGXTMEN1KMT2ANPC1 | |
| SCHEMBL2863444 | 0.75 | TP53 (0.44) | LOXL2TP53AGXTMEN1KMT2A | |
| SCHEMBL7126578 | 0.75 | MAOB (0.51) | LOXL2AGXTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |