Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075637 | 0.80 | LOXL2 (0.69) | LOXL2AGXTHTR1AHTR2BPOLB | |
| SCHEMBL10369285 | 0.75 | LOXL2 (0.53) | LOXL2AGXTHTR1AHTR2BCYP19A1 | |
| SCHEMBL11840367 | 0.75 | LOXL2 (0.53) | LOXL2AGXTMEN1KMT2AHTR1A | |
| SCHEMBL61411 | 0.74 | MAOB (0.71) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL12854020 | 0.74 | MAOB (0.71) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL103158 | 0.73 | MAOB (0.63) | MAOBMAOALOXL2RAB9AALOX5 | |
| SCHEMBL30036439 | 0.73 | MAOB (0.63) | MAOBMAOALOXL2RAB9AALOX5 | |
| SCHEMBL7806512 | 0.73 | LOXL2 (0.60) | LOXL2AGXTRAB9AMEN1KMT2A | |
| SCHEMBL19497662 | 0.72 | MAOB (0.63) | MAOBMAOARAB9AMEN1KMT2A | |
| SCHEMBL727203 | 0.72 | MAOB (0.62) | MAOBMAOARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | SHARP KABUSHIKI KAISHA (JP) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | BBOX1, DDO, OGFOD1 | MAOB 128/4885MAOA 573/4885LOXL2 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.