Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840121 | 0.77 | PNP (0.41) | PNPKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7276657 | 0.75 | CRHBP (0.60) | CRHBPCRHR2MBOAT4KDM4EALDH1A1 | |
| SCHEMBL11840115 | 0.75 | PNP (0.41) | PNPKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL11835298 | 0.73 | KDM4E (0.43) | PNPKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18796710 | 0.72 | PDE3B (0.60) | PNPKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3836372 | 0.71 | KDM4E (0.50) | CRHBPCRHR2KDM4EALDH1A1MCL1 | |
| SCHEMBL5117155 | 0.71 | CRHBP (0.54) | CRHBPCRHR2MBOAT4KDM4EALDH1A1 | |
| SCHEMBL3680667 | 0.70 | KMT2A (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL11832343 | 0.70 | DAO (0.54) | CRHBPCRHR2MBOAT4KDM4EALDH1A1 | |
| SCHEMBL18796780 | 0.70 | HSD11B1 (0.42) | KDM4EALDH1A1MCL1EEDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948903-A | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins | PARKE, DAVIS & COMPANY (US) | 1976-04-06 | — | — | US | disclosed |