Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844695 | 0.82 | CA2 (0.42) | MAPTGAACA2LMNATSHR | |
| SCHEMBL11841120 | 0.80 | MAPT (0.51) | MAPTGAAHCAR3CA2TPMT | |
| SCHEMBL2741935 | 0.77 | CA2 (0.39) | GAAHCAR3CA2LMNATSHR | |
| SCHEMBL2741850 | 0.77 | CA2 (0.59) | MAPTGAAHCAR3CA2LMNA | |
| SCHEMBL11839922 | 0.77 | MAPT (0.75) | MAPTGAAHCAR3CA2LMNA | |
| SCHEMBL11840687 | 0.76 | MAPT (0.47) | MAPTGAAHCAR3CA2TPMT | |
| SCHEMBL2879281 | 0.75 | MAPT (0.48) | MAPTGAAHCAR3CA2LMNA | |
| SCHEMBL2741851 | 0.74 | CA2 (0.58) | MAPTGAAHCAR3CA2LMNA | |
| SCHEMBL2741936 | 0.74 | CA2 (0.39) | CA2LMNATSHRKDM4EUSP2 | |
| SCHEMBL11853571 | 0.73 | CA2 (0.53) | CA2LMNATSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |