Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844669 | 0.88 | MAPT (0.57) | MAPTGAAHCAR3ALDH1A1TDP1 | |
| SCHEMBL11846149 | 0.85 | HCAR3 (0.58) | MAPTGAAHCAR3ALDH1A1PKM | |
| SCHEMBL7570478 | 0.82 | MAPT (0.92) | MAPTGAAHCAR3ALDH1A1TDP1 | |
| SCHEMBL11847155 | 0.82 | KMT2A (0.55) | MAPTGAAALDH1A1L3MBTL1PKM | |
| SCHEMBL11845733 | 0.82 | CA2 (0.56) | MAPTGAAHCAR3ALDH1A1PKM | |
| SCHEMBL11841120 | 0.80 | MAPT (0.51) | MAPTGAAHCAR3ALDH1A1POLB | |
| SCHEMBL11851335 | 0.79 | ALDH1A1 (0.58) | MAPTGAAALDH1A1L3MBTL1POLB | |
| SCHEMBL10540328 | 0.78 | MAPT (0.83) | MAPTGAAHCAR3ALDH1A1TDP1 | |
| SCHEMBL11842797 | 0.78 | HCAR3 (0.53) | MAPTGAAHCAR3ALDH1A1LMNA | |
| SCHEMBL11841111 | 0.77 | MAPT (0.48) | MAPTGAAHCAR3ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |