Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159713 | 0.79 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2CYP19A1SIGMAR1 | |
| SCHEMBL10394613 | 0.79 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2CYP19A1SIGMAR1 | |
| SCHEMBL28182243 | 0.78 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2CYP19A1SIGMAR1 | |
| SCHEMBL11832156 | 0.77 | KDM4E (0.50) | NPC1RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL8045875 | 0.77 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2CYP19A1SIGMAR1 | |
| SCHEMBL9541314 | 0.75 | FADS1 (0.69) | DDB1CRBNFADS1ACHE | |
| SCHEMBL31300377 | 0.75 | FADS1 (0.69) | DDB1CRBNFADS1ACHE | |
| SCHEMBL7272079 | 0.75 | NPC1 (0.80) | DDB1CRBNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL697728 | 0.74 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2CYP19A1ACHE | |
| SCHEMBL30721496 | 0.74 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2CYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970650-A | DRUG INTERMEDIATE | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-07-20 | — | — | US | claimed |
| US-3970650-A | DRUG INTERMEDIATE | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-07-20 | — | — | US | disclosed |