Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832940 | 0.84 | TLR8 (0.38) | ALDH1A1PLAUMEN1NPC1RAB9A | |
| SCHEMBL11833453 | 0.83 | CYP19A1 (0.39) | ALDH1A1NPBWR1PLAUL3MBTL1MAPK1 | |
| SCHEMBL11840151 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PLAUHPGD | |
| SCHEMBL11837367 | 0.82 | TSHR (0.41) | ALDH1A1TSHRNPBWR1PLAUKMT2A | |
| SCHEMBL11840566 | 0.81 | CYP19A1 (0.38) | ALDH1A1NPBWR1PLAUL3MBTL1MAPK1 | |
| SCHEMBL11832742 | 0.79 | CYP19A1 (0.36) | ALDH1A1PLAUMEN1NPC1RAB9A | |
| SCHEMBL11840001 | 0.76 | TLR8 (0.40) | ALDH1A1TSHRPLAUNPC1RAB9A | |
| SCHEMBL11845478 | 0.76 | AR (0.37) | ALDH1A1PLAUKDM4EGAAMAPT | |
| SCHEMBL11838169 | 0.74 | TLR8 (0.39) | ALDH1A1TSHRKDM4EGAAPOLB | |
| SCHEMBL11833732 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956344-A | Process for the production of substituted 2-benzoylpyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-11 | — | — | US | disclosed |