Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833453 | 0.86 | CYP19A1 (0.39) | ALDH1A1CYP19A1TLR8TLR7NPSR1 | |
| SCHEMBL11840566 | 0.85 | CYP19A1 (0.38) | ALDH1A1CYP19A1TLR8TLR7NPSR1 | |
| SCHEMBL11832742 | 0.82 | CYP19A1 (0.36) | ALDH1A1CYP19A1TLR8TLR7NPSR1 | |
| SCHEMBL11844643 | 0.82 | IMPDH2 (0.41) | TSHRALDH1A1PLAUHSD17B10L3MBTL1 | |
| SCHEMBL11840001 | 0.80 | TLR8 (0.40) | TSHRALDH1A1CYP19A1TLR8TLR7 | |
| SCHEMBL11845478 | 0.79 | AR (0.37) | ALDH1A1CYP19A1PLAU | |
| SCHEMBL11838169 | 0.78 | TLR8 (0.39) | TSHRALDH1A1TLR8TLR7NPSR1 | |
| SCHEMBL11833732 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1CYP19A1CYP2C9TDP1 | |
| SCHEMBL11832940 | 0.77 | TLR8 (0.38) | ALDH1A1TLR8TLR7CYP1A2CYP2C9 | |
| SCHEMBL11840151 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TLR8TLR7PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956344-A | Process for the production of substituted 2-benzoylpyridines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-11 | — | — | US | disclosed |