Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.70 |
| ▸ | DRD2 | P14416 | 6/20 | 0.70 |
| ▸ | HTR1A | P08908 | 5/20 | 0.70 |
| ▸ | HTR2A | P28223 | 5/20 | 0.70 |
| ▸ | DRD3 | P35462 | 5/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.70 |
| ▸ | HTR2C | P28335 | 3/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.70 |
| ▸ | HRH1 | P35367 | 3/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.70 |
| ▸ | HTR2B | P41595 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL11846805 | 0.90 | OPRM1 (0.68) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| Clopimozide SCHEMBL123100 | 0.88 | DRD2 (0.76) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| Clopimozide SCHEMBL29710914 | 0.88 | DRD2 (0.76) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL2615400 | 0.88 | DRD2 (0.81) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| Isopropyl Alcohol SCHEMBL11841622 | 0.86 | OPRM1 (0.62) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11839760 | 0.86 | DRD2 (0.78) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| Isopropyl Alcohol SCHEMBL11845667 | 0.85 | OPRM1 (0.71) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL13285211 | 0.84 | DRD2 (0.77) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| Clopimozide SCHEMBL11835033 | 0.83 | DRD2 (0.63) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL11841645 | 0.82 | DRD2 (0.72) | OPRM1DRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989707-A | NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-02 | — | — | US | disclosed |