Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562067 | 0.82 | MAPT (0.57) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL13401380 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1LMNAMAPK1TDP1 | |
| SCHEMBL6663908 | 0.71 | CA12 (0.49) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL20804137 | 0.71 | L3MBTL1 (0.61) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL17785176 | 0.69 | MAPT (0.55) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL15083665 | 0.69 | HPGD (0.55) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL9328016 | 0.69 | HPN (0.45) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL9706622 | 0.69 | ALDH1A1 (0.43) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL7905195 | 0.68 | EPHX1 (0.65) | KDM4EPOLBMAPTALDH1A1LMNA | |
| SCHEMBL111820 | 0.67 | ALDH1A1 (0.46) | KDM4EPOLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940394-A | ANTILIPEMIC | SANTILLI ARTHUR A | 1976-02-24 | — | — | US | disclosed |