Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847402 | 0.86 | TSHR (0.59) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL2493279 | 0.81 | TSHR (0.83) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11850001 | 0.81 | TSHR (0.74) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11847707 | 0.80 | TSHR (0.63) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11847929 | 0.78 | TSHR (0.60) | TSHRGAAGFERTP53KDM4E | |
| Hydrochloric Acid SCHEMBL11851095 | 0.78 | TSHR (0.73) | TSHRGAAGFERKMT2AMEN1 | |
| SCHEMBL11846615 | 0.77 | MEN1 (0.44) | TSHRGAAKMT2AMEN1CYP3A4 | |
| SCHEMBL11850698 | 0.77 | TSHR (0.59) | TSHRSOS1KMT2AMEN1TP53 | |
| SCHEMBL11847604 | 0.77 | TSHR (0.65) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11851828 | 0.74 | TSHR (0.72) | TSHRGAAGFERSOS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |