Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845463 | 0.86 | TSHR (0.57) | TSHRGAAGFERSOS1KMT2A | |
| Hydrochloric Acid SCHEMBL11851095 | 0.86 | TSHR (0.73) | TSHRGAAGFERKMT2AMEN1 | |
| SCHEMBL11850001 | 0.84 | TSHR (0.74) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11847707 | 0.83 | TSHR (0.63) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL2493279 | 0.82 | TSHR (0.83) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL578232 | 0.76 | PARK7 (0.76) | PARK7TDP1ALDH1A1ALDH3A1CHRM5 | |
| SCHEMBL29406370 | 0.76 | PARK7 (0.76) | PARK7TDP1ALDH1A1ALDH3A1CHRM5 | |
| SCHEMBL11851828 | 0.76 | TSHR (0.72) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11850946 | 0.75 | TSHR (0.70) | TSHRGAAGFERSOS1KMT2A | |
| SCHEMBL11845293 | 0.75 | TSHR (1.00) | TSHRGAAGFERSOS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |